Bluetooth com port question

In the documentation you can open a com port using CreateFile with both read and write access and you see this in a lot of sample code.
Is it any advantage to use two separate com ports or perhaps use one com port and two file handles where the com port is being heavily used for read and write operations
In my code I'm writing to a com port created with read and write access very frequently and the reads are done using polling on a separate thread (critical sections are used around the read and write calls).